All treatment guides

Polynucleotides

Regenerative treatment in clinic, supported by hydration and protection at home.

Educational guidance · official ESK prices · 10% ReGen discount

About this treatment

Polynucleotides are regenerative injectable treatments designed to support the skin's own repair processes and overall skin quality. At ReGen they are prescribed in consultation as part of a personalised plan.

Regenerative treatments work with your skin's biology over time — and that biology benefits from skin that is well hydrated, barrier-supported and protected every day.

How your daily routine complements treatment

A consistent routine complements regenerative treatment by keeping the skin hydrated and calm. Hydration in particular supports the environment the treatment is designed to improve.

Skincare supports and maintains; the treatment itself is what drives regeneration. One does not replace the other.

ESK products for general skin maintenance

Products for general skin maintenance between treatments — not for application to freshly treated areas. Follow your practitioner's aftercare before resuming products over treated areas.

  1. 1Calming Cleanse
    Calming Cleanse£35.00£31.50

    A gentle creamy soap-free cleanser. Coconut based with soothing botanicals including Aloe Vera, Lavender, Rose, Soy extract and Orchid that leaves your skin clear and hydrated. May also be used as a makeup remover.

  2. 2Hydraboost HA Serum
    Hydraboost HA Serum£63.00£56.70

    A hyaluronic acid serum with three molecular weights of HA plus panthenol for deep, lasting hydration.

  3. 3Repair +
    Repair +£69.00£62.10

    A lightweight barrier cream with niacinamide, ceramides, hyaluronic acid and panthenol to calm and hydrate dry, reactive skin.

  4. 4Zinc Shade
    Zinc Shade£50.00£45.00

    A lightweight, matte day cream with broad-spectrum SPF15 protection, built on zinc oxide 10% and designed for minimal white cast. Doubles as a make-up primer.

Actives that may need adjusting around treatment

Whether — and for how long — to adjust any product is always your practitioner's decision for your plan. No fixed timings are given here, and actives must never be applied to recently treated skin without clinical guidance.

  • —

    Retinal (vitamin A), exfoliating acids and vitamin C serums. Your practitioner will advise whether, and for how long, to adjust actives around treatment. Do not apply products to freshly injected or sensitive areas without their guidance.

Treatment aftercare comes first

The aftercare instructions given to you at ReGen are specific to the treatment protocol, the areas treated and your clinical plan. They always take priority over general routine guidance, including this page.

When to contact ReGen for personalised advice

  • ·Before a treatment course, so your routine can be reviewed alongside it.
  • ·If you are unsure whether your usual actives should be adjusted around treatment.
  • ·If you notice unexpected redness, swelling or any concern after treatment — contact the clinic.

Educational information only, pending review by our practitioner. Skincare complements — never replaces — professional treatment. Always follow the aftercare given to you at ReGen, and check official ESK product directions on each product page before use.

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